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Review Papers | Pharmaceutical Science | India | Volume 8 Issue 10, October 2019 | Popularity: 6.4 / 10

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Nanotechnology Based Drug Delivery Systems

Pankaj Rajdeo

Abstract: Nanoparticles hold huge potential as a powerful drug delivery system. In this article we talked about ongoing improvements in nanotechnology for drug delivery. To beat the issues of drug delivery, nanotechnology has picked up enthusiasm for late years. Nanosystems of various structures and organic characterisics have been widely used for drug and quality delivery applications. To accomplish productive drug delivery it is critical to comprehend the cooperations of nanomaterials with the organic condition, focusing on cell-surface receptors, drug release, etc. A several anticancer drugs including paclitaxel, doxorubicin, 5-fluorouracil and dexamethasone have been effectively formulated using nanomaterials. The various nanoparticles used for in vitro RNAi delivery are Quantom Dots, Chitosan, Polylactic/Glycolic Corrosive (PLGA) & PLGA based products. On account of the trouble in getting imaging and therapeutic agents past the blood -brain barrier and into the brain cerebral disease is one of the most troublesome malignancies to distinguish and treat. Anticancer drugs for example, loperamide and doxorubicin bound to nanomaterials have been appeared to cross the unblemished blood -brain barrier and released at remedial focuses in the brain. A recent approach to control disease progression is the utililizaton of nanomaterials as well as peptide based nanotubes to target on vascular endothelial tissue receptorts and cell adheshion molecules like integrins, cadherins & selectins.

Keywords: Nanotechnology, Doxorubicin, Barrier, Disease, etc

Edition: Volume 8 Issue 10, October 2019

Pages: 1509 - 1512

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