Evaluation of Antioxidant Activity of Pomegranate Peels Phytosome

Shital Pande, Ashwin Deshmukh

Abstract: Phytosomes are novel phytophospholipid carriers for herbal drug delivery as standardized extracts which are shows, poor bioavailability and limited clinical utility. Pomegranate fruit (Punica granatum L. ) belongs to the Punicaceae family is one of the most popular and important horticultural fruits, which contain high levels of a diverse range of photochemical including polyphenols, sugars, fatty acids (conjugated and non-conjugated), aromatic compounds, amino acids, tocopherol, sterols, terpenoids, alkaloids, etc. It has been proved that pomegranate has a high antioxidant activity and is effective in the prevention of atherosclerosis, cancer, cardiovascular disease, dental conditions, bacterial infections and antibiotic resistance, and ultraviolet radiation-induced skin damage. The objective of this study to compare the antioxidant activity of methanolic extract of obtained from pomegranate peels and its Methanolic extract-phospholipid complex (ME-PC) phytosomes. Aqueous solutions of known Fe+2 concentrations, methanolic extract of pomegranate peels and prepared phospholipid complex were used for calibration. It was found that the methanolic extract- phospholipid complex i. e. prepared Phytosomes has higher antioxidant activity than methanolic extract.

Keywords: Antioxidant, Pomegranate peels, Methanolic extract, Phytosome