Sickle Cell E Disease: A Case Report

Dr. Nishat Ahmad, Dr. M. A. Ansari, Dr. Sunil Kumar Mahto

Abstract: HbE is a variant haemoglobin that results from substitution of lysine for glutamic acid at 26th position in globin chain. It can present as homozygous state or in heterozygous state associated with other haemoglobin chain disorders or haemoglobinopathies like sickle cell anemia or thalassemia. A case of a 23 year old female who presented with signs and symptoms of anemia was investigated and was found to be a compound heterozygous case of HbSE.

Keywords: Anaemia, Haemoglobin E, globin gene, Sickle cell/Haemoglobin E disease HbSE