Non-Fluoride Agents for Enamel Remineralization

Alexander Bonchev, Marin Simeonov, Radosveta Vassileva

Abstract: In this review the potential of several candidates for remineralization of demineralized human enamel was followed within the results published through the last several decades. Remineralization of early carious lesions may be possible with a variety of currently available agents containing fluoride, bioavailable calcium and phosphate, and casein phosphopeptide in-amorphous calcium phosphate (CPP-ACP), xylitol etc. The current concept further bridges the traditional gap between prevention, non-invasive and surgical procedures which is just what dentistry needs for the current age.

Keywords: remineralizing agent, CPP-ACP, fTCP, Bioactive glass, xylitol