International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Research Paper | Medical Surgical | India | Volume 8 Issue 2, February 2019

Clinico-pathological Study of Skin Adnexal Tumours

Vaidik Shrivastava | V. M. Mulay | R. S. Bindu

Abstract: ObjectiveThe objective of this study was to study various histomorphological patterns of skin adnexal tumours with clinico-pathological correlation and to study age and sex distribution in skin adnexal tumours. also study different anatomical locations of skin adnexal tumours. material and method- 54 Skin adnexal tumors diagnosed in the department pathology at government medical college aurangabad, maharashtra, during 3 years duration between July 2014 to July 2017. All slides were stained with H & E (hematoxylin and eosin) stain. And special stain like PAS used whwnever required. Result- Out of 54 cases, 44 were diagnosed as benign and 10 as malignant tumours of skin constituting 81.48 % and 18.51 % respectively. Among all 54 cases of skin adnexal tumors, pilar differentiation constituted the maximum with 18 cases (33. .33 %) followed by tumors with eccrine glands differentiation with 16 cases (29.62 %), tumors with sebaceous differentiation 13 cases (24.09 %) & apocrine 7 cases (12.96 %). Most common age group affected was 31- 40 years. Male female ratio-1.25: 1. Head and neck was the most common site. Pilomatricoma were commonest benign tumour and sebaceous cell carcinoma were commonest malignant tumour. Conclusion- stomorphology is the most important in the diagnosis of skin adnexal tumours. scanner view is of most important for assessment of architectural features of irregular and infiltrative pattern of growth associated with necrosis to distinguish malignant features before evaluating cytological features. Among all skin adnexal tumours frequency of benign tumours is more compare to malignant ones. Skin adnexal tumours can occur anywhere in the body but head and neck region found to be the most common location.

Keywords: SAT - Skin adnexal tumours BCC - Basal cell carcinoma TE - Trichoepithelioma SCAP - Syringocystadenoma papilliferum IHC - Immunohistochemistry CEA - Carcinoembryogenic antigen EMA - Epithelial membrane antigen LMWK - Low molecular weight cytokeratin HMWK - High molecular weight cytokeratin SMA - Smooth membrane antigen PAS - Periodic acid Schiff WHO - World health organization H&E - Haematoxylin and eosin Fig - figure SMA - Smooth membrane antigen PAS - Periodic acid Schiff WHO - World health organization H&E - Haematoxylin and eosin Fig - figure MACS- Microcystic Adnexal Carcinomas

Edition: Volume 8 Issue 2, February 2019,

Pages: 898 - 902

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