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Research Paper | Cardiology Science | Bulgaria | Volume 7 Issue 11, November 2018
?arly Versus Lat? Primary Percutan?ous Coronary Angioplasty in Pati?nts with Acut?myocardial Infarction and Singl? V'ss?l Coronary Dis?as? - Factors for Ov?rall Pati?nts Survival Rat?
Plamen Krastev
Abstract: Primary percutaneous coronary intervention (PPCI) is a preferred strategy for reperfusion of the coronary artery, under ST-elevation myocardial infarction /STEMI/ conditions, if it can be done quickly by an experienced operator. Improving the left ventricular function predicts a better short-term and long-term prognosis. The aim of the study was to assess the success of primary angioplasty, depending on the time from the onset of symptoms to the use of interventrial treatment in patients with STEMI and single coronary artery disease with respect to blood flow recovery in the target artery, left ventricle systolic function, early and late major adverse cardiac events /MACE/. In the present study, 178 patients with an average age of 59.79 13.29 years in the range 32-95 years were enrolled.128 (71.9 %) of them are male and 50 (28.1 %) female patients. The population surveyed are patients from St. Ekaterina University Hospital - Sofia. The voluntary participation of all persons under examination is certified by written informed consent. The data is entered and processed with the IBM SPSS Statistics 23.0 statistical package. Patients aged 62 years or older have an 8 times higher risk of lethal outcome than younger patients; women have a 3.3 times higher risk of fatal outcome than men. The presence of chronic kidney disease increases the lethal risk by about 5.7 times; The greatest impact on survival is cardiogenic shock, which is associated with an 18 times higher mortality risk; Access via a. femoralis is associated with a 4.8 times higher risk of death than a. radialis; In our study, age, gender, presence of chronic kidney disease, dyslipidemia, atrial fibrillation, arterial access to the intervention are defined as the main prognostic factors for patient survival. Late reperfusion may increase survival benefits, especially in elderly patients.
Keywords: Primary percutaneous coronary intervention, ST-elevation myocardial infarction, Left ventricle LV remodelling
Edition: Volume 7 Issue 11, November 2018,
Pages: 26 - 29