A Fatal Outcome of Rhino-Orbital-Cerebral Mucormycosis in Newly Diagnosed Diabetic Patient

Alkhamis Mohammed, Almomen Ali, Molani Fadel, Alhubail Rasheed

Abstract: Mucormycosis is a progressively invasive disease, with a fatal outcome, on late presentation. A 37- year-old male with recently diagnosed diabetes mellitus presented with orbital cellulitis and signs of sinusitis. He underwent transnasal endoscopic debridement of paranasal sinuses. The histopathology specimen revealed the growth of mucormycosis. He was treated with intravenous (IV) amphotericin B, Posaconazole, IV insulin, and extensive debridement surgery, but had an unfavorable outcome due to rapid mucor invasion to the brain.

Keywords: Mucormycosis, diabetes mellitus, paranasal sinuses, amphotericin B, Posaconazole