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Case Studies | Medicine Science | Morocco | Volume 7 Issue 7, July 2018

Is SIRS a Predictive Factor of Mortality in Cirrhotic Patients?

A. Benayad ^[2] | S. Oubaha ^[3] | K. Krati ^[3] | Z. Semlani ^[2]

Abstract: Introduction Systemic inflammatory response syndrome (SIRS) is a common condition in patients with cirrhosis of the liver. This condition predisposes to deterioration of liver function and serious effects on the course of the disease with significant morbidity and mortality Patients and methods This is a retrospective study performed in the hepatogastroenterology department of Mohamed VI University Hospital of Marrakech over a 2-year period from 2016 to December 2017, including all cirrhotic patients whose diagnosis was was established on clinico-biological, endoscopic and morphological criteria, and who were hospitalized for decompensation of cirrhosis, the analysis was made on the data of their last hospitalization. The Child-Pugh and MELD scores were calculated, systemic inflammatory response syndrome (SIRS) was systematically sought, the statistical analysis was performed by the FISHER software in uni-varied and multi-variate analysis. Results 188 patients were cirrhotic in decompensation, of which 56 presented the SIRS (30 %) the overall mortality rate was 11 % or 18 patients, 15 of them met the criteria of SIRS. SIRS patients had a high bacterial infection prevalence (p = 0.008), and a higher prevalence of jaundice (p

Keywords: cirrhosis, SIRIS, infection, hospital mortality, prognosis

Edition: Volume 7 Issue 7, July 2018,

Pages: 40 - 44