A Randomized Study Comparing the Analgesic and Sedative Effect of Dexmedetomidine and Fentanyl with Ropivacaine for Epidural Analgesia in Patient Undergoing Percutaneous Nephrolithotomy
Abstract: Aims and Background To prolong postoperative analgesia many adjuvants has been used opioids and alpha-2 agonists are very popular among them. This study was aimed at comparing the sedative and analgesic properties of epidural administration of fentanyl and dexmedetomidine as an adjuvant to ropivacaine. Methodology With Institutional ethics committee clearance this study was conducted at our hospital. After obtaining informed and written consent, a total of 60 patients scheduled for elective percutaneous nephrolithotomy (PCNL) were randomly allocated into two groups of 30 each. Patients of both genders, aged 21-60 y, ASA physical status I and II were enrolled. Group RD received 28 ml of inj ropivacaine 0.5 % + dexmedetomidine 1 g/kg and Group RF received 28 ml of ropivacaine 0.5 % + inj fentanyl 1 g/kg epidurally. Time of first rescue analgesia, hemodynamic parameters, sedation scores were recorded. Data were compiled systematically and analyzed using unpaired t-test, Chi square and Mann-Whitney U test. P
Keywords: Epidural Anesthesia, Ropivacaine, PCNL, Dexmedetomidine, Fentanyl
How to Cite?: Dr. Varsha Kothari, Dr. Rajni Mathur, "A Randomized Study Comparing the Analgesic and Sedative Effect of Dexmedetomidine and Fentanyl with Ropivacaine for Epidural Analgesia in Patient Undergoing Percutaneous Nephrolithotomy", Volume 7 Issue 6, June 2018, International Journal of Science and Research (IJSR), Pages: 785-788, https://www.ijsr.net/getabstract.php?paperid=ART20183267, DOI: https://dx.doi.org/10.21275/ART20183267