Comparison of Butorphanol Versus Fentanyl on Intraoperative Anaesthesia Course and Post-Op Recovery Characteristic in Patient Undergoing Laparoscopic Surgery

Dr. Bhavna H.Sojitra, Dr. Deepali L Patel, Dr. Pragna Vachharajani

Abstract: AIMS AND OBJECTIVES Primary-To compare the analgesic efficacy of fentanyl and butorphanol, Secondary-To compare recovery characteristic of fentanyl and butorphanol MATERIAL AND METHODS After approval from institutional ethical committee 60 patients were randomly divided to 2 groups, FENTANYL GROUP Inj. fentanyl 2ug/kg iv given 4min before induction BUTORPHANOL GROUP Inj. butorphanol 15-20 ug/kg iv given 4min before induction. Rescue analgesia Inj. Diclofenac sodium 1.5 mg/kg sos in both groups. EXPECTED RESULTS Butorphanol and fentanyl both are cardiostable, but there is significant fall in heart rate and blood pressure observed in patients who received butorphanol as premedication compared to the patients who received fentanyl. CONCLUSION Butorphanol and Fentanyl both are cardio stable. But less haemodynamic variations are observed in the Butorphanol group. Recovery time in Butorphanol group is prolonged (6.13 min) when compared to Fentanyl group (3.42 min) Post operative sedation and analgesia remained for longer duration in Butorphanol group. Thus considering analgesia and haemodynamics, it is concluded that Butorphanol is better than Fentanyl.

Keywords: BUTORPHANOL