Synthesis of Coumarin Derivatives and Antimicrobial Activities against E-Coli

V. Narmadhadevi

Abstract: Due to exceptional reactivity of coumarin, the synthesis of new coumarin derivatives type has been carried out. The newly synthesized derivatives contain different functional groups, and as such they could exhibit microbiological activity. Therefore, the microbiological activity of these derivatives on E-Coli is tested. The tested compounds have shown different activity in terms of growth inhibition of microorganisms.

Keywords: Coumarin derivatives, Disc diffusion technique, antibacterial activity, E-Coli, minimum inhibitory concentrations