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Research Paper | Chemistry | Volume 6 Issue 4, April 2017 | Pages: 267 - 269 | India
RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs?Aceclofenac
Abstract: A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of ACECLOFENAC. Isocratic elution at a flow rate of 1.2 ml /min was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile 0.1M Acetic Acid 6040 (v/v). The UV detection wavelength was at 210 nm. Linearity was observed in concentration range of 0.01-0.05 gm/ml. The retention time for ACECLOFENAC was 3.0 min. The method was validated as per the ICH guidelines. The proposed method can be successfully applied for the estimation of ACECLOENAC.
Keywords: Aceclofenac, Method Development, Validation, 210nm
How to Cite?: Dr. Bhaskarrav N. Makwana, "RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs?Aceclofenac", Volume 6 Issue 4, April 2017, International Journal of Science and Research (IJSR), Pages: 267-269, https://www.ijsr.net/getabstract.php?paperid=ART20172291, DOI: https://dx.doi.org/10.21275/ART20172291