International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 123 | Views: 198

Research Paper | Microbiology | India | Volume 6 Issue 3, March 2017

Antiglycemic Activity of Endophytic Fungi from Selected Medicinal Plants by Alpha-Amylase Inhibition Method

Kamana Sahani | Deependra Thakur | K.P.J. Hemalatha | Arkajit Ganguly

Abstract: The aim of this work was to evaluate the inhibitory activities of ethylacetate extracts of endophytic fungi isolated from tulsi and aloe vera by alpha amylase inhibition method. Diabetes mellitus is a clinical condition characterized by hyperglycemia in which an elevated amount of glucose circulates in the blood plasma. Alpha amylase inhibitors are used to achieve greater control over hyperglycemia in type 2 diabetes mellitus. The present study intends to screen novel alpha amylase inhibitors from natural sources like endophytic fungi from medicinal plants in order to minimize the toxicity and side effects of the inhibitors currently used to control hyperglycemia.

Keywords: Endophytic fungi, Tulsi, Aloe vera, Ethyl acetate, Secondary metabolites, alpha amylase inhibition

Edition: Volume 6 Issue 3, March 2017,

Pages: 2203 - 2206

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