Comparative Evaluation between Blend from Beta-Sitosterol and Chitosan with Ration (2:1) and Rosuvastatain on Plasma Lipid Profile Changes in Hypercholesetrolemic Rabbits
Abstract: The purpose of the present survey was to determine the effects of the Blend from -Sitosterol and Chitosan with ration (21) and rosuvastatain on plasma lipid profile changes and the influence of time on treatment process in rabbits. For the management of cholesterol induced hyperlipidemia. Eighteen healthy rabbits were randomly divided into three equal groups Group A (control) included six rabbits that were fed with cholesterol powder (0.5 g/kg B. W for 2 weeks). Group B was similar group A, but in addition rosuvastatain (0.4mg/kg) was administrated for 4 weeks after induced hyperlipidemia. Group C was similar to B, but blend (0.07g/kg B. W) was administered instead of rosuvastatain. Blood samples were collected from ear margin vein by using insulin syringe (2ml) and transferred into EDTA tubes immediately. Blood was then centrifuged at (402 Xg for 10 minutes) to remove red blood cells and recover plasma, this plasma sample was used in biochemical measurements total cholesterol TC, triglycerides TG, high density lipoprotien HDL levels were measured using standard commercial Kits. Rosuvastatain (p
Keywords: Rosuvastatain, Rabbits, Hypercholestermic, Lipid profiles, -Sitosterol, chitosan, Passiflora incarnata L
How to Cite?: Nadhum A. Awad, Adnan J. M. Al-Fartosy, Nisreen A. Abdul A. Aali, "Comparative Evaluation between Blend from Beta-Sitosterol and Chitosan with Ration (2:1) and Rosuvastatain on Plasma Lipid Profile Changes in Hypercholesetrolemic Rabbits", Volume 5 Issue 12, December 2016, International Journal of Science and Research (IJSR), Pages: 2080-2084, https://www.ijsr.net/getabstract.php?paperid=ART20163888, DOI: https://dx.doi.org/10.21275/ART20163888