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M.Tech M.E PhD Thesis | Medicine Science | Volume 5 Issue 7, July 2016 | Pages: 1006 - 1011 | Iraq
The Anti-angiogenic Activity of Matricaria Chamomilla Flowers Extraction
Abstract: Background The Matricaria chamomilla is widely used in Asian countries as the traditional medicine to treat various diseases. Objective The possible anti-angiogenic activity of Matricaria chamomilla flowers extracts was aimed to be investigated. Subjects and methods The powder of the Matricaria chamomilla flowers was extracted sequentially with petroleum ether, chloroform, methanol and water using the cold method maceration as extraction process. The ex vivo rat aorta ring assay was used to screen the extracts for possible antiangiogenesis activity, this assay was also used to determine the doseresponse effect of the active extract by preparing serial concentrations. Free radical scavenging activities of the extracts were determined using 1, 1diphenyl2picrylhydrazyl) assay (DPPH) Results The obtained data revealed that the four extracts exhibited significant inhibition of blood vessels growth when they were compared to the negative control (received DMSO 1 %) (P
Keywords: Anti-angiogenesis, Matricaria chamomilla, free radical scavenging activity
How to Cite?: Adeeb A. AL-zubaidy, Hayder B Sahib, Safaa H. Ganduh, "The Anti-angiogenic Activity of Matricaria Chamomilla Flowers Extraction", Volume 5 Issue 7, July 2016, International Journal of Science and Research (IJSR), Pages: 1006-1011, https://www.ijsr.net/getabstract.php?paperid=ART2016316, DOI: https://dx.doi.org/10.21275/ART2016316