International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
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Research Paper | Toxicology Science | Volume 5 Issue 10, October 2016 | Pages: 29 - 32 | Nigeria


Effect of Carmoisine Orally Administered on Thyroid Hormones and Thyroid Stimulating Hormone of Albino Rats

Ibioku Elekima, Ollor Amba Ollor

Abstract: The effect of carmoisine orally administered on thyroid hormones and thyroid stimulating hormone on albino rats were evaluated. Thirty rats (30) weighing approximately 0.14kg were used for the experiment. The rats were divided into five groups namely 1, 2, 3, 4 and 5. Each group consist of six (6) rats. When the T3, T4 and TSH were analysed statistically, results obtained showed that Group 1 (control 0.0g/kg) had 0.2200 0.0609, 2.185 0.4687 and 0.7933 0.541 for TSH, T4 and T3 respectively. Group 2 (0.07g/kg) had 0.1887 0.0723, 2.847 0.7020 and 1.332 0.4913 for TSH, T4 and T3 respectively. Group 3 (0.11g/kg) had 0.3767 0.3051, 2.438 0.2255 and 1.375 0.5023 for TSH, T4 and T3 respectively. Meanwhile, Group 4 (0.14g/kg) had 0.1017 0.0279, 3.012 0.4185 and 1.087 0.4628 for TSH, T4 and T3 respectively. Finally, Group 5 had 0.0933 0.0378, 3.4370 0.5896 and 1.688 0.6748 for TSH, T4 and T3 respectively. The comparison of Group 1 and Group 2 (table 4.1) and group 1 and Group 3 showed no significant differences in TSH, T4 and T3 (p

Keywords: Thyroxine T4, Triiodothyronine T3, Thyroid stimulating hormone TSH, Carmoisine,

How to Cite?: Ibioku Elekima, Ollor Amba Ollor, "Effect of Carmoisine Orally Administered on Thyroid Hormones and Thyroid Stimulating Hormone of Albino Rats", Volume 5 Issue 10, October 2016, International Journal of Science and Research (IJSR), Pages: 29-32, https://www.ijsr.net/getabstract.php?paperid=ART20161782, DOI: https://dx.doi.org/10.21275/ART20161782

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