International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
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Research Paper | Biochemistry | Volume 2 Issue 9, September 2013 | Pages: 185 - 189 | Nigeria


The Impact of Zidovudine (An Antiretroviral Drug) on Some Serum and Erythrocyte Biochemical Parameters in Wistar Albino Rats

Okonkwo C.O, Uwakwe A.A.

Abstract: Zidovudine (AZT) is a nucleoside analog, a reverse transcriptase inhibitor (NRTI) and a type of antiretroviral drug used for the treatment of HIV/AIDS. The administration of zidovudine to the wistar albino rats showed an increase in erythrocyte fragility as can be seen from figure 1. There were significant (p0.05) decrease in serum ALP activity, significant (p

Keywords: zidovudine, nucleoside analog, reverse transcriptase, inhibitor, antiretroviral

How to Cite?: Okonkwo C.O, Uwakwe A.A., "The Impact of Zidovudine (An Antiretroviral Drug) on Some Serum and Erythrocyte Biochemical Parameters in Wistar Albino Rats", Volume 2 Issue 9, September 2013, International Journal of Science and Research (IJSR), Pages: 185-189, https://www.ijsr.net/getabstract.php?paperid=03091301, DOI: https://dx.doi.org/10.21275/03091301

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