International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Anaesthesiology | India | Volume 9 Issue 1, January 2020


A Prospective Comparative Study between 10ml & 15ml of Normal Saline for Epidural Volume Expansion, with 10mg of 0.5% Intrathecal Hyperbaric Bupivacaine for Elective Surgeries Up to Umbilical Level in Adult Patients

Dr Vinay Kumar Kirla | Dr M. Santhi Sree [2] | Dr B. Sowbhagya Lakshmi


Abstract: INTRODUCTION: The Epidural Volume Expansion (EVE) technique is a modification of CSE, Study is aimed to compare the two Normal saline volumes (NS) (10ml and 15ml) for EVE on spinal anaesthesia with 10 mg of 0.5% hyperbaric bupivacaine for elective surgeries up to umbilical level, with respect to sensory, motor blockade and haemodynamics Methodology: 90 patients of both sexes, aged between 18-60 years, with ASA grade I & 2, are taken and divided into 3 groups, A, B, C (n=30) Group A received 2ml of 0.5% Bupivacaine intrathecally without EVE. Group B received 2ml of 0.5% hyperbaric Bupivacaine and EVE of 10ml NS, and Group C received 2ml of 0.5% hyperbaric Bupivacaine and EVE with 15ml NS. The data obtained was analysed using Cramer's V test, Independent T-test and Anova RESULTS: Maximum level of a sensory blockade is seen in Group C. Time for two-segment regression maximum in Group B, Duration of Anaesthesia is highest in Group B, Duration of Motor Blockade is highest in Group B. Bradycardia, hypotension more in Group C. CONCLUSION: EVE of 10 ml of saline with intrathecal 0.5% Bupivacaine is better compared to EVE of 15 ml of saline with regard to sensory and motor block and hemodynamic stability


Keywords: Epidural, Combined spinal-epidural, Epidural volume expansion


Edition: Volume 9 Issue 1, January 2020,


Pages: 1708 - 1711


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How to Cite this Article?

Dr Vinay Kumar Kirla, Dr M. Santhi Sree, Dr B. Sowbhagya Lakshmi, "A Prospective Comparative Study between 10ml & 15ml of Normal Saline for Epidural Volume Expansion, with 10mg of 0.5% Intrathecal Hyperbaric Bupivacaine for Elective Surgeries Up to Umbilical Level in Adult Patients", International Journal of Science and Research (IJSR), Volume 9 Issue 1, January 2020, pp. 1708-1711, https://www.ijsr.net/get_abstract.php?paper_id=ART20204421

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