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Case Studies | Medicine Science | United States of America | Volume 7 Issue 8, August 2018

Idiopathic Granulomatous Hepatitis Presented as Fever of Unknown Origin

Abstract: Granulomatous hepatitis is a well-known cause of fever of unknown origin [1, 2, 3]. This syndrome is characterized by hepatic granulomas and nonspecific flu-like symptoms, fever, and weight loss, or by asymptomatic liver function abnormalities [4]. Most common causes include viral hepatitis, Mycobacterial infections, Q fever and histoplasmosis. Certain malignancies e. g. lymphomas and drugs/ toxins are also associated with the development of granulomatous hepatitis. Recent studies have shown that in 5-30 of cases, granulomatous hepatitis is idiopathic with no obvious secondary cause [5]. Steroids are very safe and effective for symptomatic treatment in most cases. Moreover, in some cases, like ours, long-term steroid treatment is needed [6].

Keywords: MCV Mean cell corpuscular volume, ACE Angiotensin converting enzyme, IVC Inferior vena cava, AST Aspartate aminotransferase, ALT, Alanine aminotransferase, HIV Human Immunodeficiency virus, LFT Liver function tests, PBC Primary biliary cirrhosis

Edition: Volume 7 Issue 8, August 2018,

Pages: 1463 - 1465