International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 108

Research Paper | Medical Science | India | Volume 7 Issue 11, November 2018


The State of the System of Matrix Metalloproteinases and of their Tissue Inhibitors in Patients with Metabolic Syndrome

Magapu Veera Venkata Akhil [2]


Abstract: Metabolic syndrome (MS) is a disease with a complex aetiology. Its main signs include hypertension, insulin resistance, obesity and dyslipidaemia. Since MS is associated with the involvement of heart and blood vessels, the researchers pay great attention to the role of extracellular matrix (EM) in the processes of geometric remodelling of myocardium in patients with cardiovascular system disorders. Thus, we have defined a significant role of MMP-1 and TIMP-1 system in the EM remodelling in patients with MS. In patients with MS and AH associated with metabolic disorders, such as IR and OB, decreased plasma MMP-1 and increased TIMP-1 are accompanied by myocardial extracellular matrix remodelling with subsequent formation of left ventricular geometry of a certain type.


Keywords: metabolic syndrome, system of matrix metalloproteinases, myocardial remodelling, arterial hypertension


Edition: Volume 7 Issue 11, November 2018,


Pages: 1459 - 1461


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Magapu Veera Venkata Akhil, "The State of the System of Matrix Metalloproteinases and of their Tissue Inhibitors in Patients with Metabolic Syndrome", International Journal of Science and Research (IJSR), Volume 7 Issue 11, November 2018, pp. 1459-1461, https://www.ijsr.net/get_abstract.php?paper_id=ART20192593

Similar Articles with Keyword 'metabolic syndrome'

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Review Papers, Medical Science, Albania, Volume 11 Issue 9, September 2022

Pages: 548 - 551

Aletration of Lipid Profile in Rheumatoid Arthritis

Artan Shkurti [2] | Gentjan Stroni

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Doctoral Thesis, Medical Science, India, Volume 12 Issue 5, May 2023

Pages: 314 - 318

Study of Thyroid Dysfunction in Patient with Metabolic Syndrome in a Tertiary Care Centre of Kumaon Region

Swati Chamoli | Makrand Singh | Gaurav Yadav [2]

Share this Article
Top