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Research Paper | Gynaecology | Turkiye | Volume 7 Issue 9, September 2018

The Impact of Maternal Iodine Status during Pregnancy on Maternal and Perinatal Outcomes

Erbil Cakar | Sevcan Arzu Arinkan

Abstract: Objectives The objective of this study was to assess the impact of maternal iodine status during pregnancy on maternal and perinatal outcomes. Material and Methods This retrospective study was conducted on 295 healthy pregnant women who were attended routine antenatal clinic at Zeynep Kamil Maternity and Pediatric Research and Training Hospital in May 2013 and May 2014. Spot urine samples were collected in order to measure iodine levels. An iodine level below 150 g/L was considered as iodine deficiency. The cases were grouped according to their urine iodine levels. Statistical Package for the Social Sciences (SPSS, Version 20.0, Chicago, IL, USA) was used for statistical analyses. Results Mean maternal age was 296 years, mean neonatal birth weight was 3290545 grams and mean urinary iodine level was 7958 g/L.271 cases (91.9 %) were defined as iodine deficient. Preeclampsia was determined in 19 cases (6.4 %) and 16 of them were in iodine deficient group. Gestational diabetes were determined in 30 cases (10.2 %) and 28 of them were in iodine deficient group.14 cases were required neonatal intensive care unit (NICU) follow up and 13 of them were in iodine deficient group. There were no statistically significant difference between the groups for mode of delivery, preeclampsia, gestational hypertension, gestational diabetes mellitus and need for NICU (P=0, 106, 0, 207, 0, 547, 0, 756, 0, 889). Mean neonatal serum TSH level was 3, 42, 1 mIU/L in iodine deficient group and 4, 32, 2 mIU/L in without iodine deficient group. There were no statistically significant difference between groups in neonatal serum TSH levels (P=0, 310). There were also no correlation between maternal urinary iodine level and birth weight and neonatal serum TSH levels. Conclusion We concluded that there were no increased risk in adverse maternal and neonatal obstetric outcomes in iodine deficient cases if TSH levels were in normal limits. So we do not offer routine iodine replacement in pregnancy if they were not living in endemic iodine deficient areas.

Keywords: Pregnancy, thyroid, iodine deficiency, pregnancy outcomes

Edition: Volume 7 Issue 9, September 2018,

Pages: 469 - 472

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