International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

Evaluation of Anti-mitotic and Cytotoxic Potential of Methanolic Extract of Balanus amphitrite

Neha Bhavnani, Shashank More, Bhagyashree Ghag, Madhavi Indap

Abstract: Balanus amphitrite of phylum Arthropoda, Class Crustacea and family Balanidae are sessile invertebrates found in tropical and sub-tropical regions. They are traditionally looked upon as fouling agents. Our present study examines the cytotoxic and anti-mitotic activity of methanolic extract of Balanus amphitrite (BME) using MTT assay and Allium cepa root tip assay respectively. BME was found to be cytotoxic to Lung cancer cell line (A-549) with IC 50 value of 242g/ml and significantly anti-mitotic on Allium cepa root tip cells.

Keywords: Barnacle, cytotoxicity, anti-mitotic activity, MTT, Allium cepa assay