ISSN: 2319-7064
Z. Tribak, M. K. Skalli, O. Senhaji, Y. Kandri Rodi
Abstract: We report in this paper the reaction of 1, 3-Dipolar Cycloaddition between azides and 5-chloro-1- (prop-2-yn-1-yl) indoline-2, 3-dione in order to synthesize new cycloadducts. The configuration of the products obtained was determined by the magnetic resonance of the proton and carbon. A theoretical study was also carried out, based on the DFT-B3LYP calculation method. The results are in agreement with experimental regiochemistry.
Keywords: 5-chloro-1- prop-2-yn-1-yl indoline-2, 3-dione, dipolarophile, 1, 3-Dipolar Cycloaddition, theoretical study, DFT