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Review Papers | Pharmaceutical Science | India | Volume 14 Issue 2, February 2025 | Rating: 5 / 10
Development and Evaluation of Mouth Dissolving Anti - Inflammatory Tablet Containing Fenoprofen
Sweety Verma, Dr. Alka Verma
Abstract: The aim of this study was to formulate and evaluate a mouth - dissolving tablet of Fenoprofen, a nonsteroidal anti - inflammatory drug (NSAID), for rapid onset of action and improved patient compliance. Fenoprofen is known for its anti - inflammatory, analgesic, and antipyretic characteristics, but its conventional dosage forms have restrictions such as delayed onset of action and gastrointestinal irritation. In this work, we develop mouth - dissolving tablets using good excipients, add super disintegrants, make sure rapid disintegration and drug release. The tablets were analysed for various physicochemical variable such as disintegration time, drug content, in - vitro dissolution, and stability. The results shows that the improve formulation exhibited excellent disintegration and dissolution characteristics, with a significant upgrade in drug bioavailability correlate to standard formulations. The advanced mouth - dissolving tablets showed promise as a well - found alternative for delivering Fenoprofen in an efficient and patient - friendly manner.
Keywords: Mouth - Dissolving Tablet, Fenoprofen, Anti - Inflammatory, NSAID, Drug Delivery, Super disintegrants, Formulation, Evaluation, Dissolution, adherence
Edition: Volume 14 Issue 2, February 2025,
Pages: 1160 - 1162