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Analysis Study Research Paper | Reconstructive Surgery | India | Volume 14 Issue 2, February 2025 | Rating: 5.1 / 10
Efficacy of Platelet Rich Plasma in Chronic Wounds Assessed by using PWAT and VAS Score
Dr. Juhi Singhal, Dr. Priyanka Sant, Dr. Deep Shikha
Abstract: Introduction: Chronic wound present a substantial obstacle in the field of healthcare, necessitating effective treatment methods to facilitate healing and reduce the economic burden. Objective: This study aims to compare the efficacy of platelet-rich plasma (PRP) dressings with conventional wound dressings in the treatment of chronic wounds. Method: A randomized controlled study was conducted over 18 months in the Department of Surgery at S.N. Medical College, Agra. Patients with chronic wounds were assessed, and wound characteristics were documented. Weekly dressing analyses were performed on days 1, 7, 14, 21, and 28, with wound size and photographs recorded using the photographic wound assessment tool (PWAT). Result: The results showed that PRP dressings were more effective in reducing wound size, with a decrease from 67.67 cm? (?86.05) to 43.12 cm? (?53.33) by the end of the fourth week (p = 0.913). Both groups experienced significant pain reduction over time (p < 0.001), but PRP dressings demonstrated superior pain alleviation. The average total PWAT score was lower for the PRP group (11.31 ? 2.46) compared to the conventional dressing group (16.00 ? 2.35), with a p-value < 0.001, indicating the overall effectiveness of PRP dressings. Additionally, PRP dressings were more effective in minimizing necrotic tissue. Conclusion: The study concluded that PRP dressings are superior to conventional wound dressings in terms of reducing healing duration, decreasing pain, promoting healing, and minimizing necrotic tissue content in chronic wounds. But due to the limited sample size, a bigger study is recommended to come to a definitive conclusion.
Keywords: platelets Rich Plasma, Chronic Wounds, PWAT, VAS
Edition: Volume 14 Issue 2, February 2025,
Pages: 864 - 869