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Analysis Study Research Paper | Otorhinolaryngology | India | Volume 13 Issue 12, December 2024 | Rating: 5.4 / 10
A Study on Efficacy of Platelet Rich Plasma in Tympanoplasty and Myringoplasty
Dr. Diksha Singh Baghel, Dr. Yashveer Jk, Dr. Smita Soni, Dr. Barkha Singh
Abstract: Aims: To evaluate the Graft takeup, bone conduction and complications in patients with inactive mucosal type of chronic otitis media disease. Material and methods: The study was conducted as prospective study on patients with chronic otitis media with having central perforation in pars tensa with dry middle ear cavity, presenting to the Department of Otorhinolaryngology, Hamidia Hospital, Bhopal for tympanoplasty and myringoplasty, during the study period of 18 months. Myringoplasty or tympanoplasty was done by a single senior surgeon and PRP was prepared at the time of placing graft. All the patients were followed up at 1 month, 2 month and 3 months after surgery and were observed for closure and healing of tympanic membrane using otoendoscopy. At each follow up, pure tone audiometry was also done and findings were documented. Results: We found graft uptake in 90.9%, 98.2% and 98.2% cases at 1 month, 2 month and 3 months respectively. Mean time for graft uptake was 25.44?3.71 days. Overall PTA and ABG improved over the period of 3 months (p<0.05). We observed graft displacement in 1 case (1.8%). Complications in the form of discharge and residual perforation was noted in 1 case (1.8%). Conclusions: Use of platelet rich plasma in type 1 tympanoplasty improve the graft uptake rate and promote fast recovery and reduce the risk of graft displacement. Due to presence of various growth factors, PRP aid in closure of tympanic membrane and improve the audiological outcome in terms of pure tone audiograms and air bone gap.
Keywords: PRP, myringoplasty, perforation, inactive CSOM, graft uptake
Edition: Volume 13 Issue 12, December 2024,
Pages: 940 - 946