Rate the Article: Difference Expression of Galectin-3 in Various Depth of Invasion on Colorectal Adenocarcinoma in RSUP Sanglah Denpasar, IJSR, Call for Papers, Online Journal
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 118 | Views: 369

Research Paper | Medical Science | Indonesia | Volume 8 Issue 5, May 2019 | Rating: 6.6 / 10


Difference Expression of Galectin-3 in Various Depth of Invasion on Colorectal Adenocarcinoma in RSUP Sanglah Denpasar

Johana Sensy Leni Manna, I Gusti Ayu Sri Mahendra Dewi, Ni Luh Putu Iin Indrayani Maker, Anak Agung Ayu Ngurah Susraini, Herman Saputra


Abstract: Colorectal carcinoma is the fourth leading dead of malignancy in the world, including Indonesia. The depth of invasion is one of the major prognostic factors. Galectin-3 is one of the markers that are involved in anti-apoptosis, cell adhesion, and various mechanism, such as survival, angiogenesis, proliferation, transformation, and cell migration. The purpose of this study was to determine the role of galectin-3 in depth of invasion of colorectal carcinoma. This study used analytic cross-sectional method. Forty-five samples were selected from adenocarcinoma NOS by proportional stratified random sampling. Re-diagnosis was carried out to determine depth of invasion, followed by immunohistochemical staining of galectin-3 that performed at Sentra Diagnostik Patologi Bali Laboratory. Data were analyzed by One Way Anova and Chi-square test with a value of p


Keywords: galectin-3, depth of invasion, colorectal adenocarcinoma, immunohistochemistry


Edition: Volume 8 Issue 5, May 2019,


Pages: 2053 - 2056



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