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Research Paper | Cardiology Science | India | Volume 3 Issue 6, June 2014 | Rating: 6.7 / 10
The Predictability of Apo B; Apo AI; ApoB/ApoAI as better Markers for CAD in South Indian Population
G. Kannan, N.N. Rajendran, J.S.N.Murthy, N.Vanitha Rani
Abstract: Aim: To evaluate the association of non conventional risk factors for atherosclerosis ApoB; ApoAI and ApoAI/ApoB ratio in patients with and without CAD in comparison to conventional lipid parameters; hsCRP levels and Insulin resistance. Methods: A case-control study on 125 subjects each of 35-65 years of age; with and without CAD; confirmed by coronary angiogram was conducted and the levels of serum hsCRP; ApoB and ApoAI were estimated. Pearsons correlation was done to find the association of ApoB; ApoAI; and their ratio with other cardiovascular risk factors. Multivariate logistic regression analysis was used to estimate the effect of ApoB; ApoAI on CAD; controlling the other confounders. ROC analysis was done to calculate the sensitivity and specificity of ApoB; ApoAI and ApoAI/ApoB ratio for CAD. A value of P
Keywords: apolipoproteins, CAD, biomarkers, lipids, diabetes mellitus
Edition: Volume 3 Issue 6, June 2014,
Pages: 240 - 249