Downloads: 131
Case Studies | Pathology | India | Volume 4 Issue 10, October 2015
LBC Diagnosis of Clear Cell Adenocarcinoma of Vagina: An Interesting Case Report
Dr. Preeti Agarwal | Dr. Pooja Gupta [4] | Dr. Sameer Gupta | Dr. Renu Singh | Dr. Madhu Mati Goel
Abstract: Clear cell Adenocarcinoma (CCA) of vagina is a rare malignancy, reported at early ages in daughters of mothers exposed to diethylstilbestrol (DES) in utero. Histological features are well established, however cytological findings and moreover Liquid Based Cytology (LBC) morphology is not well characterized. We report a case of primary vaginal CCA first time picked up on LBC smear examination, confirmed by further histopathology and immunohistochemistry. In this case LBC smear from a 27-year-old lady (with no maternal history suggestive of DES exposure) displayed multiple three-dimensional groups of atypical cells with abundant foamy to vacuolated cytoplasm with focal acinar formations. Subsequent histologic features from the polypoidal lesion from vagina were consistent with CCA confirmed by immunohistochemistry. This case emphasizes the role of LBC in detection of the lesion and stresses on the unique features of CCA.
Keywords: Clear cell Adenocarcinoma CCA of vagina, Cytology, Liquid Based Cytology
Edition: Volume 4 Issue 10, October 2015,
Pages: 1228 - 1231
Similar Articles with Keyword 'Cytology'
Downloads: 0
Case Studies, Pathology, India, Volume 11 Issue 6, June 2022
Pages: 906 - 908An Accidental Finding of Microfilaria in Malignant Pleural Effusion
Dr. Afreen Fatima | Dr. Pratima Singh | Dr. Dipti Tripathi | Dr Sanjay Agarwal
Downloads: 0
Research Paper, Pathology, India, Volume 11 Issue 10, October 2022
Pages: 606 - 609Gastric Aspirate: A Screening Tool for Detection of Early Neonatal Sepsis - A Prospective Study in Tertiary Care Centre
Dr. Mansi Gupta | Dr. Vivek Singh Kirar