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Research Paper | Chemistry | Iraq | Volume 5 Issue 4, April 2016
Synthesis and Characterization of New 1, 3, 4-Thiadiazoles Substituted with Imidazolidine Moiety
Qasim Mehdi Ismael | Faez Abdul-Hussien Alrammahi | Zeid Hassan Abood [2]
Abstract: 2-amino-5-mercapto-1, 3, 4-thiadiazolewas introduced in condensation reactions with both terephthaldehyde and 4-dimethylaminobenzaldehyde to yield imine derivatives1a and 1b respectively. The resulting imine1awas treated with amino acids L-valine and L-cysteine, also the imine 1b wasreacted with amino acids L-cysteine, L-isoleucine and L-tyrosine to obtain five new imidazolidine derivatives2a-erespectively.2-amino-5-mercapto-1, 3, 4-thiadiazolewas also converted to the corresponding azoaldehyde derivative3 through coupling reaction of its diazonium salt with 4-hydroxybenzaldehyde dissolved in sodium hydroxide solution. The resulting azoaldehyde 3 was reacted with2-amino-5-mercapto-1, 3, 4-thiadiazoleto give the corresponding azoimine derivative 4. Treatment of the resulting azoimine 4 with amino acids glycine, L-valine and L-cysteine afforded three new imidazolidine derivatives5a-crespectively.
Keywords: thiadiazoles, imines, imidazolidines
Edition: Volume 5 Issue 4, April 2016,
Pages: 536 - 542
Similar Articles with Keyword 'imines'
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Research Paper, Chemistry, Iraq, Volume 5 Issue 10, October 2016
Pages: 1741 - 1749Microwave Synthesis and Preliminary Antibacterial Activities of New 5-Substituted-2-thiol/thione-1,3,4- Oxadiazoles Containing the Oxazepine and Oxazepane Moieties
Zeid Hassan Abood [2] | Osama Hameed Rasheed | Majid Jari Mohammed
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Research Paper, Chemistry, India, Volume 4 Issue 8, August 2015
Pages: 1003 - 1009Synthesis, Characterization and Antimicrobial Studies on Some Trivalent Lanthanide Metal Complexes with a Bidentate O, N Donor Mixed Ligands
V. D. Ingale | N. R. Dighore | V.G.Shinde | A. S. Rajbhoj | S. T. Gaikwad