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Research Paper | Medicine Science | India | Volume 4 Issue 12, December 2015
A Clinico-pathological Study of Cases of Pemphigus
Dr. Jayesh Shah [2] | Dr. Devendra Parmar [2]
Abstract: In pemphigus, autoantibodies form against desmoglein. Desmoglein forms the glue that attaches adjacent epidermal cells via attachment points called desmosomes. When autoantibodies attack desmogleins, the cells become separated from each other and the epidermis becomes unglued, a phenomenon called acantholysis. This causes blisters that slough off and turn into sores. In some cases, these blisters can cover a significant area of the skin. Histopathological evaluation of biopsies received from the department of Dermatology. Results A total number of 400 skin biopsies were received, out of which 32 cases were of the pemphigus group of diseases. Pemphigus vulgaris accounted for 81 % (26) of cases and pemphigus vegetans accounted for 6 % ( 3) of cases. The less common types were pemphigus erythematosus and IgA pemphigus constituting 6 % ( 3) of the cases. Pemphigus vulgaris formed the most common variant.
Keywords: Pemphigus, Vulgaris, Cinicopathological
Edition: Volume 4 Issue 12, December 2015,
Pages: 242 - 243
Similar Articles with Keyword 'Vulgaris'
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Comparative Studies, Medicine Science, India, Volume 4 Issue 3, March 2015
Pages: 1736 - 1738Comparative Efficacy of Electrosurgery with Topical 50% Trichloroacetic Acid in Treatment of Warts
Harika C [2] | Sankeerth V
Downloads: 132
Research Paper, Medicine Science, Albania, Volume 4 Issue 11, November 2015
Pages: 665 - 671Systemic Inflammation in Psoriasis Vulgaris (Study of hs-CRP and alfa-TNF in Albanian Psoriatic Patients)
Migena Vargu [2] | Petrit Vargu | Nevila Heta | Eliverta Kondi | Mimoza Lezha [2]