Synthesis, Characterization of Spectral, Thermal and Antimicrobial Studies of Aminopyrimidine Schiff Base Ligand and Their Cr (II) and Fe (III) Complexes

D. T. Sakhare

Abstract: The new transition metal complexes of Cr (II) and Fe (III) were prepared from bidentate Schiff base. The Schiff base ligand synthesized from the condensation of P - bromobenzaldehyde and 2 - amino - 4 - hydroxy - 6 - methylpyrimidine (L) in alcohol medium. These metal complexes were characterized on the basis of their micro analytical data, molar conductance, magnetic susceptibility, IR, UV - Vis, 1H NMR, X - ray diffraction, thermogravimetric analysis. The ligand and their metal complexes were screened for fungicidal activity against various fungi like Aspergillus niger, Penicillium chrysogenum, Fusarium moneliforme and Aspergllus flavus. The antibacterial activity against various bacteria like Escherichia coli, Salmonellatyphi, Staphylococcus aureus, B. subtilis. The result indicated that the complexes exhibited good antifungal and antibacterial activities.

Keywords: Schiff bases, Transition metal complexes, Thermal analysis, Powder X - ray diffraction, Antimicrobial activity

How to Cite?: D. T. Sakhare, "Synthesis, Characterization of Spectral, Thermal and Antimicrobial Studies of Aminopyrimidine Schiff Base Ligand and Their Cr (II) and Fe (III) Complexes", Volume 14 Issue 2, February 2025, International Journal of Science and Research (IJSR), Pages: 1345-1351, https://www.ijsr.net/getabstract.php?paperid=MS25222083442, DOI: https://dx.doi.org/10.21275/MS25222083442