Toxic Impact of Oke-Afa Closed Landfill Leachates on Albino Mice (Musmusculus Linnaeus, 1758)

Leachates are known to be produced during and after landfill operation. There is limited information on the toxic effect of closed landfill leachate on tissues and organ of mammals. The aim of this study was to evaluate the toxic effect of Oke-Afa closed landfill leachates on Musmusculus. Twenty-five female mice were used; the mice were divided randomly into 5 groups of 5 animals each. Group 1 was the control; the other four groups were given 5-25 % concentrations of the leachate. Animals were sacrificed after 28 days; organs and blood were collected for histopathological, biochemical, and haematological analyses. Significant decrease (P