Synthesis, Characterization and Antimicrobial Studies of Mn(II), Ni(II) and Cu(II) Mixed Ligand Complexes Derived from Isatinphenylhydrazone and Nitrogen / Sulphurmonodentate Ligands

Iniama G. E, Olanrele O. S., Iorkpiligh T. I.

Abstract: A Condensation reaction of isatin and phenylhydrazine yielded the primary ligand- isatinphenylhydrazone which combined with the metal (II) ions and the secondary ligands to give the metal (II) mixed ligand complexes. These were characterized using elemental analysis, molar conductivity, infrared and electronic absorption spectroscopy. Data obtained revealed the primary ligand to be bidentate coordinating to metal ion through NO hetero-atoms. The complexes formed are octahedrally configured existing in a 212 molar ratio of primary ligandmetal secondary ligand. The antimicrobial studies carried out show enhanced growth inhibitory activities among the complexes with copper (II) mixed ligand complexes being the most effective

Keywords: Isatinphenylhydrazone, bidentate, mixed ligand complexes, antimicrobial activities