Efficient One-Pot Synthesis of Fused Isoxazolo [5,4-b] Pyridines

Samar Chtiba, Jameleddine Khiari

Abstract: A series of substituted isoxazolo [5, 4-b]pyridines derivatives has been prepared in one step from condensation of symmetrical vinamidinium salts with 5-amino-3-methylisoxazole. This efficient synthesis has the advantages of high yields and easy operation.

Keywords: isoxazolo5, 4-bpyridines, vinamidinium salts, 5-amino-3-methylisoxazole, cyclocondensation