Synthesis, Characterization and Antimicrobial Activity of Fe (III), Zn(II), Co(II), Ni(II), Cu(II) and Mn(II) Complexes with Schiff Base Mixed Ligands

Vishal G. Shinde, Vijayanand D. Ingale, Anjali A. Rajbhoj, Suresh T. Gaikwad

Abstract: Fe (III), Zn (II), Co (II), Ni (II), Cu (II) and Mn (II) complexes of Schiff bases have been prepared and characterized by their physical, spectral and analytical data. The newly synthesized mixed ligands metal complexes having a composition [M (L1/L2) X2] where M=Fe (III), Zn (II), Co (II), Ni (II), Cu (II) and Mn (II) L1/L2= bidentate ligand (derived from salicylaldehyde, o-vanilline with P-anisidine) X=H2O shows an octahedral geometry. In order to evaluate the biological activity of Schiff bases ligands and their metal complexes. The Schiff-base ligands and their new metal complexes have been screened for their antibacterial and antifungal activity (i. e Staphylococcus aureus, Bacillus substilis, antifungal activity against Aspergillus niger, Fusarium oxysporum, Staphylococcus aureus and Bacillus substilis). The X-ray diffraction studies and monoclinic crystal structure has been proposed for the mixed ligands metal complexes.

Keywords: Mixed ligand metal complexes, biological activity, and X-ray diffraction study