Effect Of Chronic Consumption of Cannabis Sativa on Bleeding Time, Prothrombin Time and Platelet Count In Albino Rats
Abstract: The effects of chronic consumption of Cannabis sativa on bleeding time and prothrombin time was studied. Fifteen albino Wistar rats weighing 200-220g were used for the study. They were randomlyassigned into 3 groups (control, low dose and high dose), n=5. The control group was administered normal saline (0.1ml/kg) while low dose and high dose groups were administered with 0.1mg/kg and 0.2mg/kg of extracts of Cannabis sativa respectively. Orogastric mode of feeding was used for the three groups, and the feeding lasted for 28 days. All the animals were allowed free access tofeed (normal rat chow) and water. After 28 days, the animals were sacrificed and blood samples were collected for analysis using standard methods. The result showed that the bleeding time and prothrombin time were each significantly (P
Keywords: Cannabis sativa, bleeding time, prothrombin time, platelet count
How to Cite?: Obembe, A. O, Okon, V. E., Ofutet. E.O, Okpo-ene, A.I., "Effect Of Chronic Consumption of Cannabis Sativa on Bleeding Time, Prothrombin Time and Platelet Count In Albino Rats", Volume 4 Issue 7, July 2015, International Journal of Science and Research (IJSR), Pages: 2562-2565, https://www.ijsr.net/getabstract.php?paperid=SUB156992, DOI: https://dx.doi.org/10.21275/SUB156992