Endometriosis and Serum Hepcidin Levels
Abstract: Aim Endometriosis is a benign disease which takes third place in gynecological morbidity after inflammatory disease and uterine myoma. We tried to evaluate serum iron and hepcidin levels and search for a connection in occurrence of endometriosis. Data For serum hepcidin quantification we used ELISA assay.40 women, average age 25.4 4.3 were included. They were divided into two groups women with endometriosis (EM) and control group. The samples were taken in the University Hospital Michin Dom for a period of one year, 2014. We measure serum iron levels, ferritin and calculate transferrin saturation. Pearsons coefficient and Students t-test were used for evaluation of correlation and statistical significance. Results We found statistically significant differences in serum hepcidin levels between measured groups women with endometriosis had higher concentrations 57.4 8.5 g/L vs control group 20.7 2.8 g/L (r = -0.174, P
Keywords: endometriosis, hepcidin, iron overload, ferritin, inflammation
How to Cite?: Manolov V, Marinov B, Vasilev V, Tzatchev K, Hadjiev E, Bogov I, Hadjidekova S, Genchev G, Emilova R, "Endometriosis and Serum Hepcidin Levels", Volume 4 Issue 1, January 2015, International Journal of Science and Research (IJSR), Pages: 2428-2430, https://www.ijsr.net/getabstract.php?paperid=SUB15694, DOI: https://dx.doi.org/10.21275/SUB15694