Green Synthesis and Characterization of Some Substituted Dihydroxychalcones

Dr. A. R. Semwal, Kusum Lata Dangwal

Abstract: The present communication, reports a series of novel chalcones synthesized from 2, 4-dihydroxy / 2, 5-dihydroxy acetophenone with substituted benzaldehydes by Claisen-Schimidt base catalyzed condensation and characterized by T. L. C. studies, elemental analysis, conductivity measurements, I. R. spectral studies. The aim of this study is to procure various dihydroxychalcone derivatives in the hope of obtaining new agents, which might show biological activities with improved potency.

Keywords: Substituted dihydroxychalcone, Microwave irradiation, Claisen-Schmidt condensation, Elemental analysis, IR spectra