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Case Studies | Medicine Science | India | Volume 4 Issue 5, May 2015

Marchiafava - Bignami Disease - A Case Report and a Brief Review of Literature

Dr. Vajed Mogal ^[6] | Dr. Sarfaraz Mohammad | Dr. Amit Rathi ^[2] | Dr. Kulin Seth

Abstract: Marchiafava - Bignami disease (MBD) is a rare neurological disorder of chronic alcoholism characterized by demyelination and necrosis of corpus callosum. Here, we report the case of an alcoholic patient with highly suspicious Marchiafava - Bignami disease who developed acute neurological dysfunction and showed characterstic abnormalities in the corpus callosum on the brain MRI. Recent advances in neuroimaging has made early diagnosis of MBD possible and helps in early initiation of treatment.

Keywords: Marchiafava - Bignami disease, Alcoholism, Corpus callosum, Sandwich sign

Edition: Volume 4 Issue 5, May 2015,

Pages: 3187 - 3190