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Case Studies | Genetics Science | India | Volume 4 Issue 5, May 2015 | Popularity: 6.1 / 10
Carcinogenesis in a Congenital Deformed Fetus - A Case Report
Uma.A.N, Baskaran.R
Abstract: USG report of a 27+3 week old female fetus in an 18 year old primi, who had undergone CT scan during her first trimester showed a Meromelia fetus. Cytogenetic studies from the cord blood cells of the medically terminated fetus revealed 48 % aberrant metaphases. The congenital deformity of the fetus could have occurred due to effects of ionizing radiation. But even more interesting were the aberrant chromosome which are the indicators of the future fatal childhood cancer that would have gone unnoticed without the chromosomal studies. The case is reported to stress the need for prenatal cytogenetic studies in an event of CT of a fetus, done either knowingly or unknowingly during the first trimester.
Keywords: CT scan, Meromelia, cytogenetics, aberrant chromosomes, prenatal diagnosis
Edition: Volume 4 Issue 5, May 2015
Pages: 1878 - 1879
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