International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Review Papers | Medicine Science | India | Volume 4 Issue 6, June 2015 | Rating: 7 / 10


Evaluation of Efficacy and Safety of a Herbal Formulation Evecare in the Management of Menstrual Irregularities: Meta-Analysis of 8 Clinical Studies

Dr. Mukta P Umarji | Dr. Jyothi.G.S.


Abstract: Aim of the study The aim is to carry out the meta-analysis of 8 clinical trials for evaluating the efficacy and safety of menstrual irregularities. Material and Methods This is a meta-analysis of 8 clinical trials on Evecare in various menstrual irregularities. Inclusion criteria Clinical studies, which evaluated the role of Evecare in various menstrual irregularities, were included in the meta-analysis. The outcome variables included measurement data on changes in clinical symptoms and signs, laboratory results, and incidence of adverse events during/after treatment. Exclusion criteria Experimental, Phase I and Phase II clinical studies were excluded from the meta-analysis. Study procedure The list of 08 clinical studies included for the meta-anlaysis is provided in Table 1. From each study, the demographic data of patients on entry was tabulated Table 2. The duration of treatment varied from 2 -3 months and in most of the studies, Evecare was given at a dose of 1-2 capsules twice daily or Evecare Syrup-10-15 ml twice daily. Summary and conclusion Present Meta -analysis of clinical studies indicate safety and efficacy of Evecare in normalizing menstrual irregularities, along with reduction in excessive menstrual bleeding and normalization of character and duration of menstrual flow. Improvement in anemia and altered hormonal levels was also noted in clinical studies.


Keywords: Evecare, meta-analysis


Edition: Volume 4 Issue 6, June 2015,


Pages: 475 - 481


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