Combination of Plasma Ultra-Sensitive CRP and Homocysteine as Diagnostic and Predictive Protocol for Acute Myocardial Infarction
Abstract: Objective The aim of the present study was to provide us-CRP test together with homocysteine test as a protocol for emergency diagnosis for acute myocardial infarction (MI) comparing to cTnI and LDL-C. Materials and Methods This was a cross-sectional study conducted in Sudan, between December 2012 and July 2014. The study included 122 patients (78 males and 44 females). All the patients were admitted in Intensive Cardiac-Care Unit (ICCU) ward, and informed consent was obtained with the blood samples immediately (within the first 3 hours after chest pain), regardless the type of that disease. Control group was consisted of 80 healthy volunteers. Using enzyme linked immunosorbent (ELISA) method we estimated serum homocysteine (Hcy), ultra-sensitivity C - reactive protein (us-CRP), and cardiac troponin I (cTnI), while low-density lipoprotein (LDL-C) is measured by Standard direct automated spectrophotometric method. During the next 24 hours, and as a result of the medical follow-up, the patients were divided into 2 groups, AMI group (68 patients) and non-AMI group (57 patients). Results The levels of us-CRP in AMI group showed significant increasing (P
Keywords: acute myocardial infarction, homocysteine, us-CRP, cTnI, LDL-C
How to Cite?: Kamal Eldin Ahmed Abdelsalam, "Combination of Plasma Ultra-Sensitive CRP and Homocysteine as Diagnostic and Predictive Protocol for Acute Myocardial Infarction", Volume 4 Issue 4, April 2015, International Journal of Science and Research (IJSR), Pages: 1733-1735, https://www.ijsr.net/getabstract.php?paperid=SUB153418, DOI: https://dx.doi.org/10.21275/SUB153418