The Prevalence of Δ508 in Cystic Fibrosis Patients with Low Bone Mineral Density in Republic of Macedonia
Abstract: Introduction Reduced bone mass density (BMD) is frequent in patients with cystic fibrosis (CF). Pathogenesis of CF bone disease is multifactorial. Many studies suggest that there is genetic component, independent of the disease severity and nutritional deficits. Aim To determine the prevalence and identify determinants of reduced BMD in CF patients. Material and methods The study included 80 CF patients (range 5-36y. ). BMD was measured via dual-energy x-ray absorptiometry (DXA) scan. Vitamin D level was assessed by plasma 25OHD levels (
Keywords: bone mineral density, cystic fibrosis, F508 genotype, vitamin D deficiency
How to Cite?: Tatjana Jakovska, Tatjana Zorcec, "The Prevalence of Δ508 in Cystic Fibrosis Patients with Low Bone Mineral Density in Republic of Macedonia", Volume 4 Issue 1, January 2015, International Journal of Science and Research (IJSR), Pages: 771-774, https://www.ijsr.net/getabstract.php?paperid=SUB15303, DOI: https://dx.doi.org/10.21275/SUB15303