Oxidative Stress Status and Lipid Level of Rats Co-Administered with Lead Acetate and Aqueous Extract of Sweet Bell Pepper (Capsicum annuum L.) Fruits
Abstract: Lead is an environmental pollutant that causes damage to biological systems. The results of in vitro analysis of methanol and aqueous extract of Capsicum annuum L. (CA) fruits showed that the aqueous extract has higher antioxidant capacity than the methanol extract. The effect of this extract on lead induced oxidative stress, organ damage and derangement of lipid metabolism was investigated in thirty five wistar rats which were divided into seven groups with five rats in each group. The lead control group was given only 740mg/kg bw lead acetate while the normal control and extract control groups were given only feed and 500mg/kg bw extract, respectively. The other groups were co-administered with Lead and varying doses of the aqueous extract of CA fruits for a period of four weeks. It was observed that there was significant (*p
Keywords: Lead Acetate, Capsicum annuum L, Lipid Peroxidation, Oxidative Stress, Hyperlipidemia
How to Cite?: Zubairu Maimuna, Umar Ismail, Afahakan Mfonobong, Sallau Balarabe, "Oxidative Stress Status and Lipid Level of Rats Co-Administered with Lead Acetate and Aqueous Extract of Sweet Bell Pepper (Capsicum annuum L.) Fruits", Volume 4 Issue 1, January 2015, International Journal of Science and Research (IJSR), Pages: 934-941, https://www.ijsr.net/getabstract.php?paperid=SUB14630, DOI: https://dx.doi.org/10.21275/SUB14630