DNA Microarray and its Applications in Disease Diagnosis

Dr. Sanjeev Singh, Megha Kadam Bedekar

Abstract: With rapid advances in the bioinformatics, computational biology, robotics and fabrication of high quality glass slides, microarray technology is increasingly being used in different laboratories all over the world. A microarray is a collection of microscopic spots arranged in an array on grid- like format and attached to a solid surface or membrane. Each individual spot is present at a precisely defined location on the substrate. In DNA microarray these spots are single stranded DNA fragments. These spots are known as probes. On basis of fluorescenc generated by spots overall gene expression is assessed. gene expression gives a comparative study of healthy and diseased condition. Microarray facilitates us with global analysis of healthy and diseased condition

Keywords: microarray, gene expression, genome, transcriptome

How to Cite?: Dr. Sanjeev Singh, Megha Kadam Bedekar, "DNA Microarray and its Applications in Disease Diagnosis", Volume 3 Issue 12, December 2014, International Journal of Science and Research (IJSR), Pages: 1572-1573, https://www.ijsr.net/getabstract.php?paperid=SUB14580, DOI: https://dx.doi.org/10.21275/SUB14580