Sepsis-Associated Acute Kidney Injury Among Hospitalized Patients: A Hospital-Based Observational Study

Dr. Vedant Lalchandani, Dr. Lokesh MR

Abstract: Background: Sepsis is a major cause of morbidity and mortality among hospitalized patients and frequently results in multi-organ dysfunction. Acute kidney injury (AKI) is one of its most serious complications, leading to prolonged hospitalization, increased need for renal replacement therapy, and higher mortality. Early recognition of AKI in patients with sepsis is essential for improving clinical outcomes. Objective: To evaluate the correlation between sepsis and acute kidney injury among hospitalized patients in a tertiary care centre and to assess the association of AKI severity with clinical outcomes. Methods: This prospective observational study was conducted over 18 months at Sri Siddhartha Medical College and Hospital, Tumakuru. Sixty-five adult patients diagnosed with sepsis according to Sepsis-3 criteria were enrolled. AKI was diagnosed and staged using the KDIGO classification. Clinical, laboratory, and outcome data, including SOFA score, dialysis requirement, length of hospital stay, and mortality, were analyzed using Epi Info version 3.4.3. A p-value

Keywords: Sepsis, Acute Kidney Injury, KDIGO, SOFA score, Dialysis, Mortality

How to Cite?: Dr. Vedant Lalchandani, Dr. Lokesh MR, "Sepsis-Associated Acute Kidney Injury Among Hospitalized Patients: A Hospital-Based Observational Study", Volume 15 Issue 8, August 2026, International Journal of Science and Research (IJSR), Pages: 439-442, https://www.ijsr.net/getabstract.php?paperid=SR26806203126, DOI: https://dx.doi.org/10.21275/SR26806203126

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