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Original Research | Medicine | Volume 15 Issue 8, August 2026 | Pages: 90 - 93 | India
Decoding Acute Kidney Injury: A KDIGO-Based Outcome Study in a Rural South Indian Tertiary Intensive Care Unit
Abstract: Acute Kidney Injury (AKI) is a common complication among critically ill patients and is associated with significant morbidity and mortality. Data on AKI in rural, low-resource settings remains limited. This study aimed to evaluate the causes, severity (based on KDIGO criteria), management, and outcomes of AKI in ICU patients at a rural tertiary care hospital in South India. Methods: A prospective observational study was conducted over 18 months having a sample of 100 ICU patients diagnosed with AKI. Patients with Chronic Kidney Disease and those discharged against medical advice were excluded. Various parameters including Clinical features, Laboratory parameters, KDIGO staging, Treatment modalities provided (dialysis, inotropes, ventilation) and the outcomes were recorded and analyzed using SPSS Version 29. Prognosis was categorized as ?Good? (shifted to ward or discharged) or ?Poor? (deteriorated or expired). Results: The majority of patients were male (65%) and above 50 years of age (63%). Sepsis was the most common etiology (46.4%), followed by cardiac causes (29.5%) among non-infective cases. Based on KDIGO classification, 41% were Stage 1, 24% Stage 2, and 35% Stage 3. Dialysis was required in 29% of patients, 47% needed invasive ventilation, and 54% required inotropes. The mortality rate was 36%. Poor outcomes were significantly associated with advanced KDIGO stages, anuria, mechanical ventilation, and dialysis requirement. Conclusion: Sepsis remains a leading cause of AKI in rural ICUs. Early recognition and aggressive management, particularly in higher KDIGO stages, are crucial to improving outcomes in resource-limited settings.
Keywords: Sepsis, Acute kidney injury (AKI), Critical care, Dialysis, Intensive Care Unit (ICU), Inotropes, Kidney Disease Improving Global Outcomes (KDIGO), Serum Creatinine, Urine output
How to Cite?: Dr. Vighnajit G L, Dr. Jagadeesan R, Dr. Koyee Mohan, "Decoding Acute Kidney Injury: A KDIGO-Based Outcome Study in a Rural South Indian Tertiary Intensive Care Unit", Volume 15 Issue 8, August 2026, International Journal of Science and Research (IJSR), Pages: 90-93, https://www.ijsr.net/getabstract.php?paperid=SR26801184405, DOI: https://dx.doi.org/10.21275/SR26801184405