Downloads: 1
Review Paper | Ayurveda | Volume 15 Issue 7, July 2026 | Pages: 2018 - 2019 | India
Re-Evaluating the Concept of Visha Gunas: An Ayurvedic and Modern Toxicological Review
Abstract: Within the framework of classical Ayurvedic science, Agada Tantra functions as the primary discipline dedicated to understanding toxic substances (Visha) and managing their clinical consequences. Traditional literature characterizes Visha as any agent that induces profound systemic distress (Vishada) and rapidly compromises vital functions. The lethality of poisonous agents, even when introduced in negligible doses, stems directly from their inherent physiological qualities, termed Visha Gunas. Although ancient texts display minor differences in the exact number and clinical classification of these attributes, a critical synthesis highlights four core, ubiquitous properties: Vyavayi (unhindered physiological dispersion), Vikasi (disruption of cellular and tissue integrity), Sukshma (deep systemic penetration), and Ushna (intense metabolic/thermal aggravation). This review re-evaluates the classical theory of Visha Gunas alongside modern concepts of toxicokinetic and cellular biology. By translating classical terminology into contemporary mechanisms-such as systemic absorption, membrane passage, tissue necrosis, and oxidative stress- this paper illustrates the enduring clinical value of Visha Gunas in managing toxic emergencies and designing targeted pharmaceutical formulations.
Keywords: Agada Tantra, Visha Guna, Toxicokinetic, Vyavayi, Vikasi, Sukshma
How to Cite?: Dr. Anjum M. Shaikh, "Re-Evaluating the Concept of Visha Gunas: An Ayurvedic and Modern Toxicological Review", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 2018-2019, https://www.ijsr.net/getabstract.php?paperid=SR26724185200, DOI: https://dx.doi.org/10.21275/SR26724185200