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Review Paper | Orthopaedic Surgery | Volume 15 Issue 8, August 2026 | Pages: 40 - 46 | India
The Aging Spine Surgical Host: Frailty, Sarcopenia, Osteoporosis, and Risk Stratification in Contemporary Spine Surgery
Abstract: Older adults are increasingly offered decompression, fusion, deformity correction, and vertebral fracture procedures, yet chronological age alone is an inadequate measure of operative risk. Frailty, sarcopenia, and osteoporosis represent overlapping but distinct domains of diminished physiologic reserve, impaired muscle function, and compromised bone strength. Each domain is common in spine-surgery candidates and has been associated with adverse perioperative events, prolonged hospitalization, non-home discharge, delayed functional recovery, mechanical complications, and revision surgery. This narrative review summarizes contemporary evidence on frailty, sarcopenia, and osteoporosis in adult spine surgery and proposes a practical perioperative risk-stratification framework for clinical use. Frailty should be considered a multidimensional vulnerability state rather than a synonym for advanced age. Sarcopenia should be screened with functional tools and confirmed with muscle quantity or quality assessment when possible, with attention to Asian diagnostic criteria. Osteoporosis and osteopenia require active preoperative detection because poor bone health increases the risk of screw loosening, cage subsidence, pseudarthrosis, proximal junctional failure, adjacent fracture, and reoperation. Current evidence supports routine screening in at-risk patients, optimization of nutrition and physical function, correction of vitamin D deficiency, and consideration of bone-active therapy before major reconstructive procedures. We propose an Aging Spine Surgical Host framework that integrates frailty, sarcopenia, osteoporosis, nutrition, cognition, mobility, and surgical magnitude into four actionable grades: robust, vulnerable, high-risk, and prohibitive or modifiable high-risk. This framework is intended to improve shared decision-making, trigger prehabilitation and bone-health optimization, and help surgeons select the least morbid durable procedure. Prospective validation is required before formal prognostic use.
Keywords: Spine, Frailty, Sarcopenia, Osteoporosis, Risk assessment
How to Cite?: Dr. Nishant, "The Aging Spine Surgical Host: Frailty, Sarcopenia, Osteoporosis, and Risk Stratification in Contemporary Spine Surgery", Volume 15 Issue 8, August 2026, International Journal of Science and Research (IJSR), Pages: 40-46, https://www.ijsr.net/getabstract.php?paperid=SR26715115616, DOI: https://dx.doi.org/10.21275/SR26715115616